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Published : 2021-01-12
Vol. 64 No. 3 (2019)

Rheological and textural properties of hydrogels, containing sulfur as a model drug, made using different polymers types

Magdalena Wróblewska Joanna Słyż Katarzyna Winnicka
DOI: https://doi.org/10.14314/polimery.2019.3.6

Abstract

The preparation technology and the optimal composition of hydrogels with sulfur prepared using various types of polymers – hydroxyethyl cellulose (HEC), Carbopol 980, and sodium alginate – have been developed. Designed hydrogels were evaluated microscopically, for pH, viscosity and mechanical parameters. In addition, ex vivo bioadhesive properties of obtained hydrogels with hairless mice skin model as adhesive layer were estimated. Hydrogels with sulfur based on sodium alginate possessed the most favorable application properties and were stable at different temperature and humidity conditions during 90 days of storage.

Keywords

hydrogel ; HEC ; Carbopol 980 ; sodium alginate ; sulfur ; bioadhesion hydrożel ; HEC ; Carbopol 980 ; alginian sodu ; siarka ; bioadhezja



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Wróblewska, M., Słyż, J., & Winnicka, K. (2021). Rheological and textural properties of hydrogels, containing sulfur as a model drug, made using different polymers types. Polimery, 64(3), 208-215. https://doi.org/10.14314/polimery.2019.3.6

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