Glycopolyoxazoline-lectin interactions. Effects of ligand structure on clustering kinetics

C. Diehl; H. Schlaad

Published : 2013-09-30

Vol. 58 No. 9 (2013)

Glycopolyoxazoline-lectin interactions. Effects of ligand structure on clustering kinetics

C. Diehl H. Schlaad

Abstract

Turbidimetric measurements were used to examine the clustering of concanavalin A (Con A) with glucosylated polyoxazolines. For homopolymers, and also block copolymers, precipitation of Con Aoccured faster with longer glucoslyated chains and higher valency of the ligand. For statistical copolymers, the same trend was observed for increasing spacing between glucose residues or decreasing epitope density. Also the nature of the non-binding side chains appeared to have impact on the clustering kinetics.

Keywords

polioksazolina ; glikopolimer ; lektyna ; kinetyka tworzenia klastrów polyoxazoline ; glycopolymer ; lectin ; clustering kinetics

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Diehl, C., & Schlaad, H. (2013). Glycopolyoxazoline-lectin interactions. Effects of ligand structure on clustering kinetics. Polimery, 58(9), 650-653. Retrieved from https://ichp.vot.pl/index.php/p/article/view/772

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C. Diehl polimery@ichp.pl

Affiliation
Max Planck Institute of Colloids and Interfaces Department of Colloid Chemistry, Research Campus Golm 14424 Potsdam, Germany

H. Schlaad

Affiliation
Max Planck Institute of Colloids and Interfaces Department of Colloid Chemistry, Research Campus Golm 14424 Potsdam, Germany